E3 Journal of Medical Research
E3 Journal of Medical Research Vol. 3 (2) pp. 013-017, February 2014; © E3 Journals; ISSN 2276-9900
Comparison of Cognitive Functions between patients with thyroid dysfunction with and without astheno-emotional syndrome
Daniel Bartholomeu1 * , José Eduardo Martinelli1 , Juliana Francisca Cecato1 , José Maria Montiel1 , Marcos de Oliveira Martinelli11 Rua Chá de Frade, 131 – Mooca, São Paulo-SP, Brazil. CEP: 03178-150
*Corresponding Author E-mail: d_bartholomeu@yahoo.com.br
Accepted 22 December 2013
Abstract
In elderly, clinical status of hyperthyroidism is very similar to hypothyroidism. Only 25% of patients above 65 years present typical symptoms of hyperthyroidism. As age increases, the typical hyperthyroidism symptoms become less frequent. The objective of this study was to compare the symptomatology and cognitive performance of older adults with thyroid dysfunction with and without astheno-emotional syndrome. Methods: 57 patients were divided into 2 groups, 31 patients with diagnostic of thyroid dysfunction presenting astheno-emotional syndrome (AES), aged 60-87 years; and 26 patients with thyroid dysfunction without AES symptoms. Results: The AES group were more depressed (GDS p = 0.039) when compared to group without AES. There are significant cognitive changes between the two groups. Considers: It is suggested a longitudinal follow-up of these cases in order to uncover the reason for this difference.
Keywords: astheno-emotional syndrome; cognitive functions; thyroid dysfunction
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