Effect of Gentamicin and Amoxicillin on methicillin resistant Staphylococcus aureus (MRSA) against different time and concentrations; Comparative study of the effect of bitter leaf extract and antibiotics (gentamycin and amoxicillin) on bacterial species isolated from wound.

E3 Journal of Biotechnology and Pharmaceutical Research

E3 Journal of Biotechnology and Pharmaceutical Research Vol. 4 (6) pp. 99-102, June 2013; © E3 Journals; ISSN 2141-7474


Evaluation of antimicrobial property of Ximenia americana

M. H. Shagal1 * , D. Kubmarawa1 , J.T. Barminas1

1 Department of Chemistry, Modibbo Adama University of Technology, P.M.B.2076, Yola, Adamawa State, Nigeria
*Corresponding Author E-mail: shagal5787@yahoo.com, Tel: 08052284456
Accepted 14 May 2013

Abstract

An investigation was carried out to determine the phytochemical composition and antimicrobial activity of ethanol and water extract originating from the powdered leaves, stem-bark and roots of Ximenia americana. Phytochemical analysis showed that the plant parts contained saponins, tannins, volatile oils, phenols, flavoniods, alkaloids, glycosides and resins. Only water extract do not contain glycosides. The antimicrobial activity tests of the plant extracts on Escherichia coli, Staphylococcus aureus, Salmonella spp and Candida albicans showed that ethanol extracts had inhibitory activity on S. arueus only. Water extract showed inhibitory activity on E. coli and S. aureus but did not inhibit the growth of Candida albicans and Salmonella spp

Keywords: Ximenia americana, phytochemical composition, antimicrobial activity, alkaloids

[Download Article - PDF]