Effect of Gentamicin and Amoxicillin on methicillin resistant Staphylococcus aureus (MRSA) against different time and concentrations; Comparative study of the effect of bitter leaf extract and antibiotics (gentamycin and amoxicillin) on bacterial species isolated from wound.

E3 Journal of Biotechnology and Pharmaceutical Research

E3 Journal of Biotechnology and Pharmaceutical Research Vol. 4 (5) pp. 89-93, May 2013; © E3 Journals; ISSN 2141-7474


Effects of aqueous extract of Camellia sinensis (l.) O.kuntze on liver markers of cadmium treated rats

Neera Singh1 * , Poonam Rani1 , M Gupta1 , Nidhi Goel1 , Neeraj Tandan1

1 Environmental Endocrinology and Biomedical Research Unit, Department of Zoology, Meerut College, Meerut 250003, India
*Corresponding Author E-mail: n27singh@yahoo.com, Tel: 09412205025
Accepted 1 April 2013

Abstract

The effects of oral feeding of aqueous extract of green tea leaf on alkaline phosphatase (ALP), acid phosphatase (ACP), alanine transaminase (ALT), aspartate transaminase (AST), sugar and total proteins were studied in the liver of cadmium treated rats. In cadmium control group sugar and protein levels were decreased and ALP level was significantly (p<0.001) decreased, whereas ACP, ALT and AST levels showed increase. In the other two experiment groups, treated with cadmium and aqueous extract of green tea, the decreased level of sugar, proteins and ALP came back to normal level in both 2 mg and 4 mg Camellia sinesis dose groups. Decrease was observed in the activity of ACP, ALT and AST in 2 mg C. sinensis dose group but with higher dose of C. sinensis, that is 4 mg dose, levels of ACP, ALT and AST were normal. The results of this study indicate that the aqueous extract of green tea restores the normal activity of these marker enzymes and antioxidant present in the green tea prevent the liver injury as indicated by the levels of enzymes status

Keywords: , green tea, cadmium, alkaline phosphatase (ALP), acid phosphatase (ACP), alanine transaminase (ALT), aspartate transaminase (AST)

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