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E3 Journal of Medical Research

E3 Journal of Medical Research Vol. 1 (4) pp. 044-051, May 2012; © E3 Journals; ISSN 2276-9900

Incidence of novobiocin resistant coagulase negative staphylococcus saprophyticus in urinary tract infection in UITH, Ilorin, Nigeria

Olatunji M. Kolawole2;3 *
Department of Microbiology, University of Ilorin, Kwara State, Nigeria; Department of Biochemistry and Microbiology, University of Fort Hare, South Africa
*Corresponding Author E-mail:
Accepted 17 April 2012


Coagulase negative Staphylococcus has long been considered of little significance as a urinary tract infection. The role of novobiocin resistant coagulase-negative Staphylococcus saprophyticus in infection of the urinary tract of women of childbearing age (14-40 years; mean age = 27 years; outpatients) was investigated. Three hundred female patients between the age bracket of 14 and 40 years (mean age= 27.3 years) attending University of Ilorin Teaching Hospital were consecutively sampled and 100 healthy women of the same age bracket were recruited as the control group. Of the 300 women recruited as the study group, 188 (62.7%) of them were positive for urinary tract infection of which 11 (5.85%) were positive for S. saprophyticus. This infection rate of 188 (62.7%) is statistically significant (p<0.01). In the control group, 30 (30%) of the 100 women were positive for asymptomatic urinary tract infection. The difference between the individuals positive for UTI in the control group and that of the study group is statistically significant (p<0.01). This study has been able to establish that S. saprophyticus and other coagulase-negative Staphylococci that are often previously dismissed as culture contaminants have greater influence in urinary tract infection especially among women of childbearing age.

Keywords: Staphylococcus saprophyticus; urinary tract infection; women of childbearing age.

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