Effect of Gentamicin and Amoxicillin on methicillin resistant Staphylococcus aureus (MRSA) against different time and concentrations; Comparative study of the effect of bitter leaf extract and antibiotics (gentamycin and amoxicillin) on bacterial species isolated from wound.

E3 Journal of Biotechnology and Pharmaceutical Research

E3 Journal of Biotechnology and Pharmaceutical Research Vol. 5 (1) pp. 007-011, January 2014; © E3 Journals; ISSN 2141-7474


The profile and antimicrobial activity of the essential oil from Callistemon viminalis (Sol. Ex Gaertner) G.Don Ex Loudon leaves

Ahmed A. Gohar1 * , Galal T. Maatooq1 , Sahar R. Gadara1 , Walaa S. Aboelmaaty1
1 Pharmacognosy Department, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt
*Corresponding Author E-mail: ahmedgohar99@yahoo.com
Accepted 6 June 2013

Abstract

Hydrodistillation of the essential oil from the fresh leaves of Callistemon viminalis (Sol. Ex Gaertner) G.Don Ex Loudon afforded 0.7% (v/w) essential oil. The chemical composition of the oil was analyzed by GC/MS. Seventeen compounds representing 96.14 % of the total oil were identified. The oil was characterized by the dominance of 1,8-Cineole (66.36 %), α-pinene (20.43 %) and α-terpineol (6.65 %). The in vitro antimicrobial activity of the essential oil was studied against two bacteria and one fungus strain, using disc diffusion method. The oil was highly active against Escherichia coli and showed moderate activity against Staphylococcus aureus and Aspergillus niger when compared with the standard antibacterial gentamicin and antifungal clotrimazole.

Keywords: Callistemon viminalis, Myrtaceae, essential oil composition, antimicrobial activity.

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